KLK15

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KLK15

A gene on chromosome 19q13.3-q13.4 that encodes a serine  endopeptidase with a trypsin- and chymotrypsin-like substrate specificity, which may: activate/inactivate proteinase-activated receptors F2R, F2RL1 and F2RL3, as well as other kallikreins (e.g., KLK1, KLK3, KLK5 and KLK11); liquefy seminal clot by cleaving semenogelins SEMG1 and SEMG2 and activating KLK3; cleave desmoglein DSG1, resulting in shedding of superficial keratinocytes from the skin surface; and play a role in tumour progression by affecting growth, invasion and angiogenesis.
References in periodicals archive ?
The continued success of ACO Health Partners is particularly significant as it operates in Northeast Florida, which is known to be ranked in the top 20 percent of the most expensive healthcare markets in the United States.
Three key challenges of the Medicare Pioneer ACO program and how Steward is breaking down these barriers;
s ACO collaborative, the 2014 results were as follows, Damore noted: 50 percent of the Pioneer ACOs in Premier's collaborative achieved some level of savings, while that same percentage, 50 percent, also received shared savings payments from CMS.
Like the Pioneer ACO Model and the Medicare Shared Savings Program, ACOs that successfully reduce the cost of care may keep some of the savings.
Mellin: We are still in the early phases of ACOs, and there are many aspects of the ACO model that are still undergoing experimentation and refinement.
In the first paper they published based on their ACO survey, the authors in fact created a simple two-category taxonomy of ACOs--physician-led versus non-physician-led (Colla et al.
ACO is an Arab regional non-governmental organization that was established in 1967 and headquartered in Kuwait city.
Regional and local hospitals, physician groups, independent physicians associations and nonprofits are well represented in ACO agreements across the country.
Today, there are more than 360 ACOs serving about 5.
Those speaking at the event explained that the new manufacturing base will enable ACO to improve service across the Middle East and North Africa.
The 3,000sqm new ACO factory will be producing complete drainage systems that will power future drainage solutions in the region and enhance it with new hygienic and customised design.
Each ACO VIRTUAL session runs for 30 minutes and features Bach, Grieg, Smalley and Piazolla - chosen to maximise the audience experience.