acid phosphatase /ac·id phos·pha·tase/ (as´id fos´fah-tās) a hydrolase found in mammalian liver, spleen, bone marrow, plasma and formed blood elements, and prostate gland, catalyzing the cleavage of orthophosphate from orthophosphoric monoesters under acid conditions; determination of its activity in serum is an important diagnostic test.
acid phosphatase,
acid (as´id),
phosphatase(s) (fos´f
tās),
acid phosphatase
| acid phosphatase n. A phosphatase with optimum functioning at pH 5.4 and present in the prostate gland. |
acid phosphatase,
an enzyme found in the kidneys, serum, semen, and prostate gland. It is elevated in serum in prostate cancer and in trauma. Normal concentrations in serum are 0 to 1.1 Bodansky units/mL. See also alkaline phosphatase.
acid (as´id),
n a chemical substance that, in an aqueous solution, undergoes dissociation with the formation of hydrogen ions; pH levels range from 0 to 6.9. See also pH and acidic. Opposite: base.
acid, acetic,
n the acid of vinegar, sometimes used as a solvent for the removal of calculus from a removable dental prosthesis. See also solvent.
acid, ascorbic,
n See vitamin C.
acid, carbolic,
n See phenol.
acid, cevitamic,
n See vitamin C.
acid conditioning,
n the use of acid (such as phosphoric acid) to prepare the tooth surface for bonding of dental adhesives or enamel sealants.
acid etchant,
n an application of phosphoric acid used to prepare enamel surfaces to aid enamel sealant placement.
acid etching,
n the process of treating the tooth enamel, generally with phosphoric acid, by removal of approximately 40 mm of enamel rod to provide retention for enamel sealant, restorative material, or orthodontic bracket.
acid, folic,
n See vitamin B complex.
acid, hydroxypropionic
n See acid, lactic.
acid, lactic (hydroxypropionic acid),
n a monobasic acid, C3H6O3, formed as an end product in the intermediary metabolism of carbohydrates. The accumulation of lactic acid in the tissues is in part responsible for the lowering of pH levels during inflammatory states; that is, the drop in pH level is believed to increase bone loss level.
acid, nicotinic,
n 1. a vitamin of the B complex group and its vitamer, niacinamide, specific for the treatment of pellagra. Niacinamide functions as a constituent of coenzyme I (DPN) and coenzyme II (TPN). Nicotinic acid is found in lean meats, liver, yeast, milk, and leafy green vegetables.
n 2. an acid (C5H4N [COOH]) that forms part of the B complex group of vitamins. It acts as a cofactor in intermediary carbohydrate metabolism. It is a constituent of certain coenzymes that function in oxidative-reductive metabolic systems. With niacinamide, it is a pellagra-preventive factor. Also called
niacin, P.-P. factor, pyridine 3-carboxylic acid, vitamin P.-P.
n 2. an acid (C5H4N [COOH]) that forms part of the B complex group of vitamins. It acts as a cofactor in intermediary carbohydrate metabolism. It is a constituent of certain coenzymes that function in oxidative-reductive metabolic systems. With niacinamide, it is a pellagra-preventive factor. Also called
niacin, P.-P. factor, pyridine 3-carboxylic acid, vitamin P.-P.
acid, orthophosphoric
n See acid, phosphoric.
acid, pantothenic
n a vitamin of the B complex group, the importance of which has not been established. It is a constituent of coenzyme A.
acid phosphatase,
n an enzyme found in the kidneys, serum, semen, and prostate gland. It is elevated in serum blood levels in individuals with prostate cancer and in individuals who have recently experienced trauma.
acid, phosphoric (HPO, orthophosphoric acid),
n the principal ingredient of silicate and zinc phosphate cement liquids.
acid, pteroylglutamic,
n See vitamin B complex.
acid salt,
n a salt containing one or more replaceable hydrogen ions.
acid, strong,
n an acid that is completely ionized in aqueous solution.
phosphatase(s) (fos´f
tās),n a group of enzymes that are distributed throughout most cells and body fluids and are characterized by their ability to hydrolyze a wide variety of monophosphate esters to alcohols and inorganic phosphate.
phosphatase, acid,
n a group of phosphatases (e.g., serum, liver, prostate) with optimal activity below a pH level of 7. Elevated serum levels have been observed in metastatic breast and prostatic cancer; Paget's, Gaucher's, and Niemann-Pick diseases and in myelocytic leukemia.
phosphatase, alkaline,
n a group of phosphatases (e.g., serum, liver, bone) whose optimal activity ranges near a pH level of 9.8. Elevated blood levels occur in Paget's disease and pregnancy, whereas low levels are characteristic of dwarfism and a generalized nutritional protein deficiency.
acid phosphatase
see acid phosphatase.
acid phosphatase
A group of enzymes with broad specificity which transphosphorylates; APs are present in the prostate gland, semen, liver, spleen, RBCs, BM, platelets Ref range 0-1.1 Bodansky U ↑ Prostate CA or infarction, Paget's
disease, Gaucher's disease, multiple myeloma. See PSA.
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