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Acetylcholine |
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acetylcholine /ac·e·tyl·cho·line/ (ACh) (as?e-til-) (as?e-tel-ko´len) the acetic acid ester of choline, which is a neurotransmitter at cholinergic synapses in the central, sympathetic, and parasympathetic nervous systems; used in the form of the chloride salt as a miotic.
Acetylcholine a molecule released by neurons at the neuromuscular junction that causes muscle contraction. acetylcholine (  ·sēˈ·tl·kōˑ·lēn),n neurotransmitter that is produced in the central and parasympathetic autonomic nervous systems. It is the most prevalent neurotransmitter in the body and is crucial to arousal, learning, memory, and motor function. acetylcholine (as´  tilkō´lēn, sē´til),n 1. an acetate ester of choline that serves as a neurohumoral agent in the transmission of an impulse in autonomic ganglia, parasympathetic postganglionic fibers, and somatic motor fibers. n 2. an ester of choline actively involved as a chemical mediator at the neuromuscular junction, at autonomic ganglia, and between parasympathetic nerve endings and visceral effectors. acetylcholine the acetic acid ester of choline, normally present in many parts of the body and having important physiological functions. It is a neurotransmitter at cholinergic synapses in the central, sympathetic and parasympathetic nervous systems. It is not used clinically but it is the classical cholinergic agonist. Abbreviated ACh. acetylcholine receptors structures located at the endorgans, e.g. at the skeletal muscle fibers. The myofibers are stimulated to contract by the interaction of acetylcholine with acetylcholine receptors which are located on the motor end plate or postsynaptic sarcolemma. See also neuromuscular junction. |
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? Mentioned in | ? References in periodicals archive | |
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The drug is a selective
serotonin 5-HT4 receptor agonist which stimulates 5-HT4 receptors in
nerve plexuses in the gastrointestinal tract and has gastroprokinetic
and gastric evacuant effects by enhancing acetylcholine release. * Cary Pope, Oklahoma State University, to study the differential
toxicity of the organophosphorus pesticides chlorpyrifos and parathion,
as well as the threat agents sarin and soman, and their inhibition of
acetylcholinesterase and the accumulation of acetylcholine in a
cannulated rat brain model
Galantamine (Reminyl)--May increase neuron sensitivity to
acetylcholine, thus enhancing the effect of acetylcholine on the brain
in those patients in early or moderate stages of the disease. |
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Acetylcholine
