acetate-CoA ligase

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acetate-CoA ligase

acetyl coenzyme A synthetase

An enzyme which catalyses the reaction: ATP + acetate + CoA  AMP + pyrophosphate + acetyl-CoA, in which acetate enters metabolic pathways and forms acetyl-CoA.

a·ce·tyl-CoA li·gase

(as'ĕ-til lī'gās)
A ligase that catalyzes the reaction of acetate and CoA and ATP to form AMP, pyrophosphate, and acetyl-CoA. A key step in the activation of acetate.
Synonym(s): acetate thiokinase, acetate-CoA ligase, acetyl-activating enzyme, acetyl-CoA synthetase.