acanthamoeba infection

Acanthamebiasis

An infection by Acanthamoeba spp, which is characterised by pustules, vasculitis, granulomatous amoebic encephalitis, and granulomas of skin. It is common in immunocompromised or immunosuppressed individuals, and may lead to death.
High-risk AIDS, alcohol abuse, diabetes, immunosuppression-transplantation-related, cancer—leukaemia, lymphoma—malnutrition
Management Chlorhexidine, propamidine, miconazole nitrate

acanthamoeba infection

Infection, with various species of the genus Acanthamoeba . Acanthamoeba culbertsoni is a ubiquitous soil AMOEBA that may cause infection in people who have suffered facial injuries or who have DIABETES or LYMPHOMAS. Abscess-like masses occur in the skin, lungs, middle ear and even the brain. Infection of the CORNEA can also occur in contact lens wearers, usually from Acanthamoeba polyphaga . Acanthamoeba cysts are impervious to chlorine in concentrations up to 50 parts per million. They may therefore survive in domestic water supplies. Treatment is with AMPHOTERICIN-B.
References in periodicals archive ?
Acanthamoeba infection of the central nervous system causes chronic granulomatous amebic encephalitis (GAE), and is usually associated with patients having a pre-existing condition such as AIDS, or other chronic illnesses which contribute to an immunocompromised state.
15) Most patients with Acanthamoeba keratitis do not exhibit other systemic symptoms of Acanthamoeba infection.
Disseminated acanthamoeba infection is a rare disease characterized by widespread granulomatous infiltration of the skin and extracerebral organs; it usually occurs in immunocompromised patients.
To treat the Acanthamoeba infection, the patient was started on oral itraconazole and intravenous metronidazole; IV pentamidine was added 2 days later.
They conclude that Acanthamoeba infection rates appear to be closely related to improper maintenance and cleaning of soft lenses by users.
Evidence of Acanthamoeba infection was recently found by PCR in brain tissue of a patient with lupus, even without isolating the ameba (8).
In conclusion, Acanthamoeba infection was demonstrated by hematoxylin and eosin and immunostaining of brain tissue and PCR detection of ameba mitochondrial DNA in brain tissue.
Acanthamoeba infections are rare, but can be dangerous and threaten a person's vision if not properly detected and treated.
The complaint further alleges that marketing claims made by AMO suggesting that Easy Rub provides "enhanced protection" against Acanthamoeba infections are also false and misleading.
Centers for Disease Control (CDC) linked the solution to a large number of Acanthamoeba infections.
All of the plaintiffs allege that they contracted Acanthamoeba infections while they were using Complete[R] MoisturePlus[TM] to disinfect their contact lenses.
Given the potential seriousness of the reported Acanthamoeba infections, AMO is working in close partnership with the CDC, the FDA and others to make sure consumers are aware of the need for proper contact lens disinfection and proper lens handling.