Acanthamoeba


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Acanthamoeba

 [ah-kan″thah-me´bah]
a genus of free-living ameboid protozoa found usually in fresh water or moist soil. Certain species, such as A. castella´ni, A. poly´phaga, A. astronyx´is, and A. culbert´soni, may occur as opportunistic human pathogens, causing an acute fatal or chronic infection of the eye, brain, liver, kidney, lung, pancreas, and skin in patients with underlying disease or in immunocompromised patients.

Acanthamoeba

(ă-kan'thă-mē'bă),
A genus of free-living ameba (family Acanthamoebidae, order Amoebida) found in and characterized by the presence of acanthopodia. Human infection includes invasion of skin or colonization following injury, corneal invasion and colonization, and possibly lung or genitourinary tract colonization; a few cases of brain or central nervous system invasion have occurred, but not solely by the olfactory epithelium route of entry as with the more virulent infections caused by Naegleria fowleri. Species responsible are chiefly Acanthamoeba culbertsoni, but cases have been reported involving Acanthamoeba castellanii, Acanthamoeba polyphaga, and Acanthamoeba astronyxis. Most cases have been chronic rather than fulminating and rapidly fatal as with N. fowleri infection.
[G. akantha, thorn, spine, + Mod. L. amoeba, fr. G. amoibē, change]

Acanthamoeba

/Acan·tha·moe·ba/ (ah-kan″thah-me´bah) a genus of free-living ameboid protozoa (order Amoebida) found usually in fresh water or moist soil. Certain species, such as A. astronyxis, A. castellanii, A. culbertsoni, A. hatchetti, A. polyphaga, and A. rhisodes, may occur as human pathogens.

Acanthamoeba

[əkan′thəmē′bə]
a genus of free-living ameboid protozoa typically found in moist soil and water. The organisms may enter the body through a break in the skin or even though the nasal mucosa, olfactory nerve, and mucous membranes of the eye. It may cause severe infections, such as keratitis (eye infection that can lead to blindness especially with contact lens wearers), and systemic infections of the lung, genitourinary system, brain, and central nervous system. Disseminated cutaneous lesions caused by this organism are seen particularly in patients with AIDS. Although an infection may be fatal, cases are more commonly chronic and can persist for months.

Acanthamoeba

A genus of free-living pathogenic amoebae, which are ubiquitous in the environment, the cycle of which consists of 2 stages: a trophozoite (which is 14–40 µm in diameter) and a cyst (which has a double-layered wall with a diameter of 12–16 µm).

Sources
Tap water, dust, soil, sewage, air-conditioning units.
 
Diseases caused by:
Amoebic keratitis, acanthamoeba granulomatous encephalitis.

Acanthamoeba

A genus of free-living pathogenic amoebas Sources tap water, dust, soil, sewage, air conditioning units. See Acanthamebiasis. Cf Leptomyxid, Naegleria.

Acanthamoeba

small amebae, found in soil and water; they have been found in tissue cultures and in sporadic cases of pneumonia, general systemic infection and can produce meningoencephalitis after experimental administration. Possibly associated with granulomatous encephalitis in greyhounds. Includes A. castellani, A. culbertsoni.
References in periodicals archive ?
Doctors of optometry recommend that lens wearers take the following precautions to avoid exposing their eyes to Acanthamoeba or other flood-related eye infections:
Doctors at London's Moorfields Eye Hospital have discovered a link between tap water and the bacterium Acanthamoeba keratitis, which eats into the cornea and can even lead to blindness.
Centers for Disease Control (CDC) linked the solution to a large number of Acanthamoeba infections.
Professor John Dart and Irenie Ekkeshis informed delegates about Acanthamoeba keratitis, including of the associated risk factors such as contact lens hygiene and tap water.
Survival and growth of Francisella tularensis in Acanthamoeba castellanii.
In Vitro Data Shows OPKO's Formulation of NCT Has Promising Activity Against Acanthamoeba Keratitis, a Serious Ocular Infection-
After four years of wearing contact lenses, he was nearly blinded by the deadly bacteria acanthamoeba.
The American Academy of Ophthalmology (Academy), the Contact Lens Association of Ophthalmologists (CLAO), the Cornea Society and the American Society of Cataract and Refractive Surgery (ASCRS) urged the changes as experts report that the number of cases of microbial keratitis, particularly Acanthamoeba keratitis, among contact lens wearers remain steady, despite attempts to improve contact lens disinfection regimens over the years and voluntary recalls of contact lens solutions associated with keratitis outbreaks in 2006 and 2007.
Unusually, this article focused on the positive messages of awareness, the importance of hygiene, the avoidance of tap water and prompt recognition and treatment of Acanthamoeba keratitis by the most appropriately qualified practitioner.
pneumophila can infect and multiply within Acanthamoeba castellanii, L.
More specifically, the Complaint alleges that the Company failed to disclose and misrepresented the following material adverse facts which were known to defendants or recklessly disregarded by them: (1) that the chances of developing acanthamoeba keratitis ("AK") significantly increased for users of Complete; (2) as such, the Company would be forced to recall Complete from the marketplace due to these concerns; (3) that, as a result of the above, the Company's future sales of Complete would be materially impacted; and (4) that, as a result of the foregoing, the Company's statements about its future business operations and prospects were lacking in a reasonable basis when made.
Rub and rinse has been proven to improve effectiveness against Acanthamoeba and other microorganisms," said David Hansen, O.