isotretinoin

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isotretinoin

 [i″so-tret´ĭ-no-in]
a synthetic form of retinoic acid (13-cis-retinoic acid), used orally to clear cystic and conglobate acne.

i·so·tret·i·noin

(ī'sō-tret'i-noyn),
A retinoid used to treat severe recalcitrant cystic acne; a known human teratogen.

isotretinoin

/iso·tret·i·noin/ (i″so-tret´in-o-in) a synthetic form of retinoic acid, used orally to clear cystic and conglobate acne.

isotretinoin

(ī′sō-trĕt′n-oin′)
n.
A synthetic isomer of retinoic acid that inhibits sebaceous gland secretion and is used in the treatment of severe nodular acne. It can cause birth defects if taken during pregnancy.

isotretinoin

[-trətin′ō·in]
an antiacne agent.
indication Subject to significant restrictions, it is prescribed for the treatment of severe cystic acne.
contraindications Pregnancy or sensitivity to the medication or any of its components prohibits its use.
adverse effects A powerful teratogen, young females must be thoroughly educated about the risk of pregnancy and are often placed on birth control pills. The most serious adverse effects to users are epistaxis, cheilitis, conjunctivitis, paresthesia, dizziness, and serum lipid and hematologic disturbances. It may also lower bone mineral density, a consideration for those participating in sports. Some patients become severely depressed or psychotic, which can make them aggressive or suicidal.

isotretinoin

Retinoic acid, 13-cis retinoic acid A retinoid used to treat acne and psoriasis and may ↓ tumor development Side effects Inflammation of skin and mucosa, hepatitis

i·so·tret·i·no·in

(ī'sō-tret'i-nō'in)
A retinoid used to treat severe recalcitrant cystic acne; a known human teratogen.

isotretinoin

A RETINOID drug used to treat ACNE. The oral preparation is used under strictly controlled conditions to exclude pregnancy because of the known risks to the fetus. Brand names are Roaccutane, and, for external use Isotrex and Isotrexin.

Isotretinoin

A powerful vitamin A derivative used in the treatment of acne. It can promote scarring after skin resurfacing procedures.
Mentioned in: Acne, Skin Resurfacing

i·so·tret·i·no·in

(ī'sō-tret'i-nō'in)
A retinoid used to treat severe recalcitrant cystic acne; known human teratogen.

isotretinoin

(ī´sōtret´inoin),
n brand name: Accutane;
drug class: retinoic acid isomer, vitamin A derivative;
action: decreases sebum secretion, improves cystic acne;
uses: severe recalcitrant cystic acne.

isotretinoin

a synthetic form of retinoic acid (13-cis-retinoic acid), used in dermatology for the treatment of disorders of keratinization. It is a potent teratogen.
References in periodicals archive ?
Commenting on her treatment with Absorica, Kelly Clark said, "Living with severe recalcitrant nodular acne was challenging, I never knew when I would have a flare-up," explained Kelly.
Sun Pharma said the settlement has seen Ranbaxy, together with its partners, Cipher Pharmaceuticals and Galephar Pharmaceutical Research entering into a non-exclusive license deal with Actavis, allowing the New York-listed firm to start selling a generic version Absorica in the U.
Absorica is indicated for the treatment of severe recalcitrant nodular acne in patients 12 years of age and older.
As part of the Settlement Agreement, Cipher, Ranbaxy and Galephar have entered into a non-exclusive license agreement with Actavis under which Actavis may begin selling its generic version of Absorica in the U.
We are thrilled to make Absorica available as a valuable option for the dermatologists and patients who need treatment for severe recalcitrant nodular acne.
The acceptance of our Dermadexin(TM) submission marks Cipher's first regulatory filing with the FDA since Absorica in 2011," said Shawn Patrick O'Brien, President and CEO, Cipher Pharmaceuticals.
Absorica is currently protected by three issued patents, which are listed in the FDA's Approved Drug Products List (Orange Book), which expire in September 2021.
Product Coverage: Anti-Acne Drugs, Solodyn, Doryx, Epiduo, Absorica & Aczone
ABSORICA has become the most prescribed branded oral isotretinoin in the U.
14 Cipher: Absorica Revenue ($m), AGR (%), CAGR (%), 2012-2024
Actavis informed that based on available information, the Company believes it may be a "first applicant" to file an ANDA for the generic version of Absorica and may be entitled to 180 days of generic market exclusivity, should its ANDA be approved.
Other printable coupons available are a Linzess coupon an Absorica coupon, and a Dymista coupon.