Abnormal Involuntary Movement Scale


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Abnormal Involuntary Movement Scale

A testing instrument devised in the 1970s which is used to evaluate the severity of symptoms of tardive dyskinesia, which are divided into abnormal movements of the face and mouth, extremities, trunk, global judgement by an examiner, and dental status, including edentia, wearing of dentures.
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The pre-specified primary endpoint was the change-from-baseline in the Abnormal Involuntary Movement Scale (AIMS) at Week 6 as assessed by central blinded video raters.
Subsequent to the placebo-controlled dosing, all subjects enter a six-week open label safety extension of 50mg of NBI-98854 administered once daily with additional Abnormal Involuntary Movement Scale (AIMS) assessments.
active scores utilizing the Abnormal Involuntary Movement Scale (AIMS) at the end of week six.
The impact on the dyskinesia was assessed utilizing the Abnormal Involuntary Movement Scale (AIMS).
Safety for INVEGA was evaluated from OLE baseline to end point, in the context of a systematic review of TEAEs, clinical laboratory tests, body weight and body mass index, electrocardiograms and EPS incidence using the Simpson Angus Rating Scale, Barnes Akathisia Rating Scale and Abnormal Involuntary Movement Scale.

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