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abacavir

   Also found in: Acronyms, Wikipedia 0.01 sec.
abacavir /abac·a·vir/ (ah-bak´ah-vir) a nonnucleoside reverse transcriptase inhibitor used as the sulfate salt as an antiretroviral in the treatment of human immunodeficiency virus infection.
abacavir,
an antiviral that is a nucleoside reverse transcriptase inhibitor.
indication It is prescribed in combination with other antiretroviral agents for HIV-1 infection.
contraindication Known hypersensitivity to this drug prohibits its use.
adverse effects Hypersensitivity reactions occur in approximately 5% of patients, and can be fatal. Other life-threatening adverse effects include granulocytopenia, anemia, and lactic acidosis. Common side effects include fever, headache, malaise, insomnia, nausea, vomiting, diarrhea, anorexia, and rash.

abacavir [ah-bak´ah-vir]
a non-nucleoside reverse transcriptase inhibitor used as an antiretroviral in treatment of human immunodeficiency virus infection; administered orally as the sulfate salt.

abacavir
Ziagen, zintavir, 1592 AIDS An HIV nucleoside reverse transcriptase inhibitor–NRTI/integrase inhibitor similar to AZT Adverse effects Life-threatening allergic reactions–fever, dyspnea, rashes, intraoral blistering, nausea, headache. See AIDS, Nucleoside reverse transcriptase inhibitor, Reverse transcriptase.


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The use of d4T in first-line treatment has been phased out in the developed world owing to toxicity, but in developing countries fixed-dose combinations containing d4T are still widely used owing to the drug's low cost compared with tenofovir or abacavir.
In addition, the Dutch also halted a batch of generic drug ARV Abacavir, which was on transit from India to Nigeria, she noted, adding that "this seems to be a generalised problem and not an isolated case.
Abacavir has been linked to hypersensitivity reactions within 6 weeks of treatment initiation, including rare cases of hepatic failure [30].
 
 
 
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