AZT


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zidovudine

 [zi-do´vu-dēn]
a nucleoside analogue to thymidine, used as an antiretroviral agent in treatment of patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS); administered orally or intravenously. It was the first agent approved for such use.

AZT

Abbreviation for azidothymidine. See: zidovudine.

AZT

zidovudine.

AZT

(ā′zē-tē′)
n.
An antiviral drug, C10H13N5O4, that is a nucleoside reverse transcriptase inhibitor and is used in combination with other drugs for the treatment of HIV infection. Also called zidovudine.

AZT

a trademark for a human immunodeficiency virus inhibitor (zidovudine). Also called Retrovir.

AZT

A nucleoside analogue used with other anti-HIV agents to manage AIDS and HIV infection.
 
Adverse effects
Long-term AZT use is associated with muscle loss, nausea, anaemia, myelosuppression, oral ulcers, bone marrow damage and headache.

AZT

3'-azido-3'-deoxythimidine, zidovudine, Retrovir AIDS A nucleoside analogue, used with other anti-HIV agents to manage AIDS and HIV infection Adverse effects Long-term AZT use is associated with muscle loss, nausea, anemia, myelosuppression, oral ulcers, BM damage, headache. See AIDS, HAART.

AZT

Abbreviation for azidothymidine.
See: zidovudine

AZT

Abbrev. for azidothymidine or Zidovudine. A drug used in attempts to control AIDS. The drug is toxic but does seem to be able to prolong life. A short course of AZT has been shown to be capable of halving the incidence of transmission of HIV from mother to baby. AZT is now commonly used in combination with other anti-HIV drugs especially protease inhibitors.

AZT

Abbreviation for azidothymidine.
See: zidovudine.

AZT,

n the abbreviation for azidothymidine. See also azidothymidine.

AZT

azidothymidine.
References in periodicals archive ?
To examine the effect of AZT MDA while adjusting for malaria clusters observed on maps, we used multivariate logistic models with random effects to compare odds of prevalent malaria infection for AZT MDA treatment villages with odds for control villages.
If rationing of ABC is required at a facility, children with previous lactic acidosis or peripheral neuropathy owing to d4T or AZT should be prioritised to receive remaining ABC stocks.
About 10 years ago, biochemical studies in several laboratories established that AZT-resistant HIV-1 reverse transcriptase uses adenosine triphosphate, or ATP, which moves energy around inside the cell, to remove the AZT.
The new PMTCT regimen sees pregnant mothers receiving AZT from 28 weeks, as well as the single dose of nevirapine administered during labour.
On Sept 19, the US FDA approved several generic formulations of AZT (listed below) for the US market and for use in PEPFAR-fund ART programs in developing countries.
His book, Debating AZT, alerted President Mbeki to the toxicity issues of AZT in late 1999.
Similarly, researchers at a Brazilian university published a study in the June issue of the Journal of Acquired Immune Deficiency Syndrome that concluded that HIV-positive infants exposed to AZT were five to six times as likely to develop full-blown AIDS as HIV-positive infants who were not exposed to AZT.
Approved November 17, 1995 for combination use with AZT as a treatment option for HIV infection in adults and pediatrics patients greater than or equal to 3 months old.
In a retrospective analysis of the subgroup of patients with high viral load at baseline (greater than 100,000 copies/mL), the combination of Sustiva, AZT and 3TC also provided suppression of viral load through 48 weeks.
compared 122 HIV-negative babies who had been exposed to AZT both in the womb and during their first 6 weeks after birth with 112 healthy babies never exposed to AZT.
French researchers say using Caesarean sections during birth, coupled with the HIV-fighting drug AZT, could nearly eliminate transmission of the Aids virus from mother to child.