ATP6V0A2

(redirected from ARCL)
Also found in: Acronyms.

ATP6V0A2

A gene on chromosome 12q24.31 that encodes a subunit of H+-ATPase (also known as V-ATPase, vacuolar ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles, which is required for an array of molecular processes, including protein sorting, zymogen activation, receptor-mediated endocytosis and synaptic vesicle proton gradient generation.

Molecular pathology
ATP6V0A2 mutations cause cutis laxa type II and wrinkly skin syndrome.
Mentioned in ?
References in periodicals archive ?
As part of Strand 2 of the ARCL project, researchers have been observing IDL lessons and interviewing stakeholders in order to develop a better understanding of how students, teachers, parents/carers and others use the technology, what they feel about their engagement in IDL activities and how those experiences influence their perceptions, satisfaction, behaviours, working practices, learning process and (learning) outcomes.
ARCL will in turn initially finance those receivables through Credit Agricole Corporate and Investment Bank, with a maximum commitment of $100 million.