NCOA4

(redirected from ARA70)

NCOA4

A gene on chromosome 10q11.2 that encodes an androgen receptor coactivator that interacts with the receptor in a ligand-dependent manner to enhance its transcriptional activity.

Molecular pathology
NCOA4 to RET translocations have been associated with papillary thyroid carcinoma.
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References in periodicals archive ?
These ARA proteins (ARA24, ARA 54, ARA55, ARA70, ARA170, and ARA267) do not share structural or functional similarities, but are all potent coactivators of the AR (38).
37) Other coregulators of AR function include ARA70, p300, CBP, Tip60, ARA55, ARA54, gelsolin, Stat3, and RAC3.