APOE genotype


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APOE genotype

A genetic variant with some use in the diagnosis of Alzheimer's disease and other dementias.
See also: genotype
References in periodicals archive ?
The APOE genotype was identified by using the APOE mutation detection kit (codons 112 and 158) as developed for the Light-Cycler instrument (Table 1).
APOE genotype and allele frequencies were not significantly different from those of other published large UK studies (Table 1).
Increased understanding of the relationships among sleep apnea, APOE genotype, and hypoxia may provide significant insight into the molecular mechanisms that initiate critical pathological cascades in TBI.
The researchers developed AD risk curves for the general population, for first-degree relatives of patients with AD independent of APOE genotype, and for first-degree relatives based on their APOE genotype.
The authors noted that APOE genotype might play a more significant role beyond 2 years following an injury, particularly in vulnerable patients (for example, those with mild cognitive impairment).
Stratifying patients, based on their apoE genotype has been suggested as a way to improve these odds.
Plasma hsCRP concentration (1) and apoE genotype (2) are both important predictors of coronary artery disease (CAD) and stroke (1, 2).
Atherotech provides clinicians with a single source for the VAP Cholesterol Test and more than a dozen cardiovascular and metabolic tests, including C-Reactive Protein (hsCRP), LpPLA2, apoE genotype, NT-proBNP, Cystatin-C, T3 and T4 when TSH is abnormal, plus gamma-glutamyl transferase (GGT), a recognized cardiovascular risk biomarker.
We used PCR and restriction-fragment length polymorphism enzyme digestion (17) to analyze of the Pro12Ala sequence variant of the PPARG gene and a lightcycler (13) to determine APOE genotype.
Total cholesterol, HDL-C, TGs, and estimated LDL-C were all associated with APOE genotype.
a) Total study population APOAV, n (%) APOE genotype n (%) Ser/Ser Total 2198 (85.
In other words, knowing a patient's apoE genotype helps a doctor predict whether or not the patient would be better off on statins versus a low-fat diet, for example.