Printer Friendly
Dictionary, Encyclopedia and Thesaurus - The Free Dictionary
3,893,481,851 visitors served.
forum Join the Word of the Day Mailing List For webmasters
?
Dictionary/
thesaurus
Medical
dictionary
Legal
dictionary
Financial
dictionary
Acronyms
 
Idioms
Encyclopedia
Wikipedia
encyclopedia
?

apolipoprotein E
(redirected from APOE gene)

    Also found in: Wikipedia 0.01 sec.
apolipoprotein E,
a protein component of lipoprotein complexes found in very-low-density lipoprotein (VLDL), high-density lipoprotein, chylomicrons, and chylomicron remnants. It facilitates hepatic uptake of chylomicron and VLDL remnants and is elevated in patients with type III hyperlipoproteinemia. One form of apolipoprotein E has been linked to Alzheimer's disease.
apolipoprotein E
A 34-kD cholesterol-binding glycoprotein, which comprises 15% of VLDL; apoE maps to chromosome 19, is secreted by macrophages that mediate the uptake of lipoproteins–VLDL, HDL, LDL and cholesterol esters into cells via distinct binding domains for each receptor; apo-E has a central role in the metabolism of TG-rich lipoproteins, and mediates the uptake of chylomicrons and VLDL by the liver
Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content.
?Page tools
Printer friendly
Cite / link 		Feedback
Add definition
Mentioned in?  References in periodicals archive?   Medical browser?   Full browser?
 
The APOE gene provides instructions for making a protein called apolipoprotein E.
Chinese medical pattern discrimination and genomics by Flaws, Bob / Townsend Letter
Men with a variation in the ApoE gene were more than three times as likely to develop dementia, whereas for women this nearly doubled the risk.
Sexes face separate dementia risks - study by guardian.co.uk / guardian.co.uk
The APOE gene comes in several different forms, or alleles, but three occur most frequently: APOE [epsilon]2, APOE [epsilon]3, and APOE [epsilon]4.
Alzheimer's disease genetics by Pamphlet by: National Institute on Aging
 
 
 
Medical Dictionary
?

Terms of Use | Privacy policy | Feedback | Advertise with Us | Copyright © 2012 Farlex, Inc.
Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.