APOA2


Also found in: Acronyms, Wikipedia.

APOA2

A gene on chromosome 1q21-q23 that encodes apolipoprotein A2, a protein component of high-density lipoprotein (HDL), which is present in plasma as a monomer, homodimer or heterodimer with apolipoprotein D.

Molecular pathology
APOA2 mutations cause apolipoprotein A2 deficiency or hypercholesterolaemia.
Mentioned in ?
References in periodicals archive ?
Since its discovery, APOA2 has been a protein in search of a function (29).
Despite the scarcity of previous data supporting a role of APOA2 in regulating food intake, copious experimental evidence demonstrates a pivotal role of another apolipoprotein, APOA4, as a satiety signal (20, 21, 39, 40).
As these effects were consistently found in both men and women, we suggest a new role for APOA2 in regulating food intake.