APEX2

APEX2

A gene on chromosome Xp11.21 that encodes a weak apurinic/apyrimidinic (AP endoDNAase), which is involved in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents, and in the redox regulation of transcription factors. APEX2 has robust 3'-5' exonuclease activity on 3'-recessed heteroduplex DNA, and preferentially removes mismatched nucleotides; it also has robust 3'-phosphodiesterase-induced removal of 3'-damaged termini formed in DNA by oxidative agents. It is required for somatic hypermutation (SHM) and DNA cleavage step of class-switch recombination of immunoglobulin genes, as well as for proper cell cycle progression during proliferation of peripheral lymphocytes.
References in periodicals archive ?
Manchester-based Heyrod is currently on site at five projects in Liverpool including APEX2 (a Liverpool University academic building), Hatton Gardens (a second Liverpool University site providing accommodation), The New Royal Liverpool Hospital, a new docklands exhibition centre and Sefton Street Block 4 (a privately-owned development).
WORLDWIDE COMPUTER PRODUCTS NEWS-May 21, 2014-NXP Software's HD voice solution featured in the ZTE Blade APEX2 smartphone
V, an independent software vendor (ISV) for mobile smart devices, announced on Tuesday the incorporation of its LifeVibes VoiceExperience solution in the new ZTE Blade APEX2 Android smartphone, which enables HD compliant, wideband voice quality.
Reportedly, the ZTE Blade APEX2 is compatible with 4G LTE networks and features a 4.
A key feature of the ZTE Blade APEX2 is the HD voice call quality.
today announced that the new ZTE Blade APEX2 Android smartphone features HD compliant, wideband voice quality thanks to the incorporation of its LifeVibes VoiceExperience solution.
Nicolas Sauvage, Marketing & Sales Director, OEM Business Line, says: "The ZTE Blade APEX2 really does offer an incredible voice quality, especially when considering this is a mid-tier priced model.