APACHE II


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Acute Physiology & Chronic Health Evaluation II. A ‘second generation’ system of objective measures for predicting the outcome of critically ill patients in an ICU based on age, physiologic status and underlying health; it acts as a tool for scoring the severity of illness in patients admitted in an intensive care unit

APACHE II

Acute Physiology and Chronic Health Evaluation, a classification system for severity of disease.
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The all-cause 28-day mortality rate among this study cohort was 61% (40/66) (Table 4) and was positively associated with underlying leukemia, steroid exposure, ICU stay on the day candidemia was suspected and tested for, intubation, persistent neutropenia, high APACHE II scores ([greater than or equal to] 19), hypoalbuminemia, and breakthrough fungemia (Table 5).
2] The APACHE II score needs to be performed after 24 hours of ICU admission, however, and is not validated as a severity-of-illness score in an emergency setting.
Preexisting pulmonary disease, preinfection LOS, and APACHE II score were independent predictors of prolonged hospitalization (Table 3).
00 am), neutrophil and eosinophil counts on the day of ICU discharge, C-reactive protein (CRP) concentrations on the day of ICU discharge, elective surgical admission, chronic medical diseases as defined by the APACHE prognostic model, APACHE II score and its derived predicted mortality, and maximum and discharge Sequential Organ Failure Assessment scores (21,22) Serum CRP concentrations were measured by an immunoenzyme analyser (Hitachi 917, Tokyo, Japan) and eosinophil counts were determined by an automated method (Cell-Dyn Sapphire, Abbott Diagnostics, IL, USA) with minimal measurable eosinophil counts of 0.
The mean APACHE II score was 27 [+ or -] 10 with a calculated predicted mortality of 57%, most patients having underlying chronic disease.
Mean age was 60 (SD 20) years, and mean APACHE II score (14) was 14.
Single organ dysfunction patients with recent surgery may not be at high risk of death irrespective of APACHE II score.
Health record reviews provided the gender, age, diagnosis of diabetes mellitus, pre-existing comorbidities, preoperative HgbA1C, BMI, type of surgery, cross-clamp and CPB times, pre- and postoperative APACHE II scores, and postoperative complications.
Patients were also assessed with the Glasgow Coma Score (GCS) and the APACHE II score.
ICU nonsurvivors (n=34) had higher APACHE II and maximum SOFA scores, higher lactate concentrations, and higher first-day plasma DNA concentrations than patients who died later in the hospital (n = 33) (P = 0.
APACHE II assesses the acute severity of illness based on 12 physiological variables.
However, patient characteristics including severity of illness and APACHE II score are not well established.