ANXA2


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ANXA2

A gene on chromosome 15q22.2 that encodes annexin 2, a calcium-regulated membrane-binding protein that controls cell growth and signal transduction pathways; it also acts as an autocrine factor, which increases osteoclast formation and bone resorption.
References in periodicals archive ?
423 ANXA2 Annexin A2 Calcium-regulated membrane-binding protein Positive correlation coefficients indicate direct correlations to [log.
Immunohistochemical labeling of several genes including CDKN1A, (12) PSCA, (7,13) MMP7, (14) MUC4, (15,16) CLDN18, (17) ANXA2, (18) BIRC5, (19,20) MUC5, (7) and S100P (21) in multiple PanIN lesions has shown a progressive increase in their expression from low- to high-grade PanINs and leading into invasive cancer.
For qPCR data, we normalized all transcript abundances to the 3 genes in the saliva internal reference (SIR): ANXA2 (annexin A2), [10] RPL37 (ribosomal protein L37), and S100A8 (S100 calcium binding protein A8) (see Supplementary Methods in the online Data Supplement).