ANXA1

ANXA1

A gene on chromosome 9q21.13 that encodes annexin 1, a calcium/phospholipid-binding protein that promotes membrane fusion and is involved in exocytosis. Annexin 1 regulates phospholipase A2 activity and thus may have anti-inflammatory activity.
References in periodicals archive ?
Annexin Al (ANXA1) has been implicated in the regulation of cell proliferation and apoptosis, and its expression decreases significantly as gastric cancer progresses, which suggests the importance of ANXA1 as a negative biomarker for gastric cancer development (Yu et al.
101) Immunolabeling-based studies have reported overexpression of CTNNB1, (100) INHA, MUC6, ENO2, MUC1, (102) ANXA1, (103) CA9, (104) and SPARCL1 (105) in some of these less common exocrine neoplasms.