ANTRIN PA

ANTRIN PA

ANTRIN Photo-Angioplasty for Prevention of Peripheral Restenosis. A trial assessing the ability, if any, of motexafin lutetium (Antrin), plus photoactivation, to prevent restenosis in femoral/popliteal arteries.
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The phase I trial is intended to primarily evaluate safety of ANTRIN PA in patients with symptomatic arterial insufficiency involving the major arteries of the lower extremities.
In the second portion of the study, now being conducted at both the Mid-America Heart Institute in Kansas City, Missouri and Stanford, ANTRIN PA is being evaluated for safety and activity using increasing doses of light.