RUNX3

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RUNX3

A gene on chromosome 1p36 that encodes a member of the runt domain-containing family of transcription factors. A heterodimer of RUNX3 and a beta subunit form a complex found in a number of enhancers and promoters, and together either activate or suppress transcription. RUNX3 is a tumour suppressor which also interacts with other transcription factors. 

Molecular pathology
RUNX3 deletion or transcriptional silence may be associated with cancer.
References in periodicals archive ?
The current carbon copy AML2 paper form will stop being a valid form of pig movement reporting.
The overwhelming feedback from producers so far is that setting up the AML2 online is very straightforward and easy to use.
The new technology will also make available the largest tape storage system ever created: with AIT 3 installed, the ADIC AML2 library can store up to 7,666 TB (native) of data in a single unit.
From October 1, there will be a transitional period of six months for the phasing out of the paper-based AML2 forms.
From April 2012, the AML2 paper forms will cease to be a valid method of reporting movements.
The initial installation includes five DST 312 tape drives installed in an ADIC/Grau AML2 robotics library.
Dorothea Schiemann from the British Pig Executive (Bpex) said: "There will be a transitional period of six months for the phasing out of the paper-based AML2 forms, planned to start from October 1, 2011.