ALX1

ALX1

A gene on chromosome 12q21.31 that encodes a protein similar to one in rodents, which is required for survival of the forebrain mesenchyme; it may be involved in development of the cervix.

Molecular pathology
Mutations in the mouse homologue causes neural tube defects.
References in periodicals archive ?
The researchers previously discovered that a gene called ALX1 controls whether beaks are blunt or pointy (57V: 3/7/15, p.
La obtencion del genoma de 120 pajaros pertenecientes a las especies identificadas por Darwin y dos mas relacionadas con ellas ha permitido senalar una region del gen ALX1 compartido por todas ellas--y por otros muchos animales--que ha ido cambiando mediante un proceso diversificador en el que se han producido episodios de hibridacion.
The researchers found that blunt beaks are associated with a distinct form of a gene called ALX1.
The big effect that ALX1 alone has on beak shape is surprising because other complex traits, such as height, are controlled by many genes, each with a tiny influence, says Richard Gibbs, a geneticist at Baylor College of Medicine in Houston.