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ALLHAT

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ALLHAT
Antihypertensive & Lipid Lowering Treatment to Prevent Heart Attack Trial. An ongoing trial evaluating whether antihypertensive therapy decreases morbidity and mortality in CAD, and whether lipid-lowering in moderately hypercholestaeremic patients decreases cardiovascular morbidity and mortality
Conclusion No major differences for antihypertensives and lipid-lowering agents in fatal CHD or nonfatal MIs

ALLHAT
Cardiology An ongoing randomized, open label, multicenter trial evaluating whether antihypertensive therapy reduces M&M in CAD, and to determine whether lipid-lowering pravastatin therapy in moderately hypercholesteremic Pts reduces heart-related M&M. See Antihypertensive, Hypertension, Pravastatin.


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In the ALLHAT study, diuretic drugs were compared to angiotensin-converting enzyme (ACE) inhibitors that widen blood vessels and decrease resistance, calcium channel blockers that relax vessels by slowing the flow of calcium into the heart and alpha blockers, which also relax blood vessels.
3) In ALLHAT, however, only 27% of individuals were controlled on the initial antihypertensive medication.
 
 
 
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