ALG


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globulin

 [glob´u-lin]
any of numerous proteins that are insoluble in water or highly concentrated salt solutions but soluble in moderately concentrated salt solutions. All plasma proteins except albumin and prealbumin are globulins. The plasma globulins are separated into five fractions by serum protein electrophoresis (SPE). In order of decreasing electrophoretic mobility these fractions are the alpha1-, alpha2-, beta1-, and beta2-globulins, and the gamma globulins.

The globulins include carrier proteins, which transport specific substances; acute phase reactants, which are involved in the inflammatory process; coagulation factors; complement components; and immunoglobulins. Examples are transferrin, a beta1-globulin that transports iron, and alpha1-antitrypsin, an acute phase reactant that inhibits serum proteases. The gamma globulin fraction is almost entirely composed of immunoglobulins.
accelerator globulin factor V, one of the coagulation factors.
antihemophilic globulin (AHG) factor VIII, one of the coagulation factors.
antilymphocyte globulin (ALG) the gamma globulin fraction of antilymphocyte serum; used as an immunosuppressant in organ transplantation. The term is sometimes used interchangeably with antithymocyte globulin.
antithymocyte globulin (ATG) the gamma globulin fraction of antiserum derived from animals (such as rabbits) that have been immunized against human thymocytes; an immunosuppressive agent that causes specific destruction of T lymphocytes, used in treatment of allograft rejection. The term is sometimes used interchangeably with antilymphocyte globulin.
bacterial polysaccharide immune globulin (BPIG) a human immune globulin derived from the blood plasma of adult human donors immunized with Haemophilus influenzae type b, pneumococcal, and meningococcal polysaccharide vaccines; used for passive immunization of infants under 18 months of age.
cytomegalovirus immune globulin a purified immunoglobulin derived from pooled adult human plasma selected for high titers of antibody against cytomegalovirus; administered intravenously for treatment and prophylaxis of cytomegalovirus disease in transplant recipients.
gamma globulin
hepatitis B immune globulin (HBIG) a specific immune globulin derived from plasma of human donors with high titers of antibodies against hepatitis B surface antigen (HBsAg); used for postexposure prophylaxis following contact with HBsAg-positive materials, also administered to infants of HBsAg-positive mothers.
hyperimmune globulin any of various immune globulin preparations especially high in antibodies against certain specific diseases.
immune globulin
2. a concentrated preparation containing mostly gamma globulins, predominantly IgG, from a large pool of human donors; used for passive immunization against measles, hepatitis A, and varicella and for treatment of hypogammaglobulinemia or agammaglobulinemia in immunodeficient patients, administered intramuscularly. See also immune g. intravenous (human).
immune globulin intravenous (human) a preparation of immune globulin suitable for intravenous administration; used in the treatment of primary immunodeficiency disorders and idiopathic thrombocytopenic purpura, and as an adjunct in the treatment of Kawasaki disease and the prevention of infections associated with chronic lymphocytic leukemia, bone marrow transplantation, and pediatric human immunodeficiency virus infection.
immune human serum globulin immune globulin (def. 2).
immune serum globulin immune g. (def. 2).
pertussis immune globulin a specific immune globulin derived from the blood plasma of human donors immunized with pertussis vaccine; used for the prophylaxis and treatment of pertussis.
rabies immune globulin a specific immune globulin derived from plasma of human donors hyperimmunized with rabies vaccine; administered in conjunction with rabies vaccine in cases of bite or scratch exposure to known or suspected rabid animals.
respiratory syncytial virus immune globulin intravenous a preparation of immunoglobulin G from pooled adult human plasma selected for high titers of antibodies against respiratory syncytial virus; used for passive immunization of infants and young children.
Rh0(D) immune globulin a specific immune globulin derived from human blood plasma containing antibody to the erythrocyte factor Rh0(D); used to prevent Rh-sensitization of Rh-negative females and thus prevent erythroblastosis fetalis in subsequent pregnancies; administered within 72 hours after exposure to Rh-positive blood resulting from delivery of an Rh-positive child, abortion or miscarriage of an Rh-positive fetus, or transfusion of Rh-positive blood. It is also used as a platelet count stimulator in the treatment of idiopathic thrombocytopenic purpura.
serum g's all plasma proteins except albumin, which is not a globulin, and fibrinogen, which is not in the serum. The serum globulins are subdivided into alpha-, beta-, and gamma-globulins on the basis of their relative electrophoretic mobilities.
specific immune globulin a preparation of immune globulin derived from a donor pool preselected for high antibody titer against a specific antigen, such as hepatitis B immune globulin.
tetanus immune globulin a specific immune globulin derived from the blood plasma of human donors who have been immunized with tetanus toxoid; used in the prophylaxis and treatment of tetanus.
thyronine-binding globulin (TBG) (thyroxine-binding globulin) an acidic glycoprotein that is the main binding protein in the blood for thyroxine, and less firmly for triiodothyronine.
vaccinia immune globulin a specific immune globulin derived from the blood plasma of human donors who have been immunized with vaccinia virus smallpox vaccine; used as a passive immunizing agent.
varicella-zoster immune globulin (VZIG) a specific immune globulin derived from plasma of human donors with high titers of varicella-zoster antibodies; used for prevention or amelioration of varicella in immunocompromised patients exposed to the disease and in neonates whose mothers develop varicella in the perinatal period.

ALG

Abbreviation for antilymphocyte globulin.

ALG

antilymphocyte globulin.

ALG

abbreviation for antilymphocyte globulin. See antithymocyte serum.

ALG

Antilymphocyte globulin, see there.

ALG

antilymphocyte globulin.
References in periodicals archive ?
Founded in 2013 by Ashley Austin, Nicole Ihasz and Cathleen Ihasz, ALG strives to preserve the integrity of its clients' legacies while simultaneously elevating profile and generating revenue in new and relevant ways.
The IAF has since been entrusted with the responsibility of developing the ALGs in Arunachal Pradesh with the dual purpose of giving a boost to local area development and enhancing military capabilities," said Air Marshal S Varthaman.
ALG brings NLC services and resources right into city vast and opens the door to the vast resources of the Internet.
Mainstream consumers have discovered what some have known for years: when it comes to low depreciation, high value performance, road gripping All Wheel Drive and high residual values, Subaru is the brand of choice," said Eric Lyman, vice president of industry insights for ALG.
Vehicle quality, production levels relative to demand, and pricing and marketing strategies represent key factors that impact ALG s residual value forecasts.
The results also indicated that adding POPL to microcapsules improved the average viability of the encapsulated probiotic bacteria by more than 1 log CFU per mL, compared with ALG microcapsules, after two hours of exposure to acidic conditions.
Since the national roll-out in September last year, more than 20,000 have received ALG, exceeding expectations and making it hugely successful.
Based in Santa Barbara, California, ALG is a leading provider of data and consulting services to the automotive industry.
ALG tabulates results separately for domestic manufacturers' cars and trucks/SUVs due to the wide perception gap that exists between these two categories.
We had a delinquency rate of close to 70% at the peak of the recession, but now we are financially stable thanks to ALG recovering close to a half a million dollars for our association, with no out-of-pocket fees.
ALG, the industry benchmark for residual values and depreciation data, has recognised the 2013 Audi Q7 with the Residual Value Award.
For the eighth year, ALG has also included awards for the brands with the highest overall predicted resale values among all mainstream and all luxury vehicles.