ABCD1

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ABCD1

A gene on chromosome Xp28, which encodes a member of the superfamily of ATP-binding cassette (ABC) transporters, which transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies—ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White. The ABCD1 protein product belongs to the ALD subfamily and is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in peroxisomes.

Molecular pathology
ABCD1 mutations are linked to adernoleukodystrophy.
References in periodicals archive ?
The Planning Committee selected a variety of topics to be addressed at ALDP workshops.
Mentors and ALDP participants typically have 8 hours of contact each month, some in one-on-one meetings.
Sergeant roles and responsibilities: How to prepare the next layer of the organization for integration into the employee development model that was created for ALDP.
The involvement of top managers ensured that the program participants have easy access to mentors, without which ALDP would have just been a succession of workshops.
To supplement ALDP and other leadership courses is a shadowing program in which junior personnel are paired with NGA and non-NGA senior leaders.