ALDH1A3

(redirected from ALDH6)

ALDH1A3

A gene on chromosome 15q26.3 that encodes an aldehyde dehydrogenase that plays a major role in detoxifying aldehydes generated by alcohol metabolism and lipid peroxidation, either in a free or cellular retinol-binding protein form.
References in periodicals archive ?
Retinol and alcohol dehydrogenases convert the sequestered retinol to retinal, which is then converted to RA by retinal dehydrogenases such as ALDH6 (Rexer et al.
The predominant linkage to RAR is through upregulation of ALDH6 and CFP1A 1, which synthesize RA.
The network depicted in Figure 2 was developed to test the hypothesis of a linkage between dioxin-responsive genes CYP1A1 and ALDH6, and the RAR-signaling gene RARB.