ALDH3A2


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ALDH3A2

A gene on chromosome 17p11.2 that encodes an aldehyde dehydrogenase that plays a major role in detoxifying aldehydes generated by alcohol metabolism and lipid peroxidation. The ALDH3A2 gene product catalyses the oxidation of long-chain aliphatic aldehydes to fatty acid.

Molecular pathology
ALDH3A2 mutation causes Sjögren-Larsson syndrome.