ALDH1A3

ALDH1A3

A gene on chromosome 15q26.3 that encodes an aldehyde dehydrogenase that plays a major role in detoxifying aldehydes generated by alcohol metabolism and lipid peroxidation, either in a free or cellular retinol-binding protein form.
References in periodicals archive ?
Supporting this hypothesis, tumor samples excised from the treated animals exhibited higher expression of DDIT3 and lower levels of ALDH1A3, an isoform of aldehyde dehydrogenase found to be over expressed in pemetrexed + cisplatin resistant MPM cells, which augments the chemosensitizing effect of butein (Canino et al.
A STAT3-NFkB/DDIT3/CEBP[beta] axis modulates ALDH1A3 expression in chemoresistant cell subpopulations.
HOXA9, ISL1 and ALDH1A3 methylation patterns as prognostic markers for nonmuscle invasive bladder cancer: array-based DNA methylation and expression profiling.