AKT1

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AKT1

A gene on chromosome 14q32.32|14q32.32 that encodes protein kinase B (PKB), a serine-threonine protein kinase that is rapidly and specifically activated by platelet-derived growth factor through phosphatidylinositol 3-kinase. PKB plays a key role in regulating cell survival, insulin signalling, angiogenesis, tumour formation and growth factor-induced neuronal survival. Activated AKT1 phosphorylates and inactivates components of the apoptotic machinery.
References in periodicals archive ?
AKT is one of the first proteins to come online, a central switch that turns on the memory factory.
Those patients who presented with acute intestinal obstruction and perforation as well as those with stricture and hypertrophic forms of tuberculosis not responding to AKT were subjected to either emergency laparotomy while those who presented with subacute intestinal obstruction were subjected to initial bowel preparation and were followed up with laparotomy.
This complex is involved in regulating the remodeling of actin in the cytoskeleton and has recently been identified as the kinase that phosphorylates AKT at residue Ser47327.
He added, "Our Singapore branch has been at the forefront of this deal, which saw us competing with a number of other global financial institutions and we are glad to have emerged as the partner of choice for AKT.
Murugov, a founder of production house and AKT member Lean-M--in which he retains a stake--adds: "We have to (control) cost of actors and crew, and use the opportunities of technology to cut costs.
The protein AKT could hold the key to future treatments for bowel cancer.
The authors of the research identified AKT as a strong lead for drug development to treat bowel cancer.
Rockey's study showed that reducing the GRK2 production restored AKT production, allowing nitric oxide levels to stabilize and blood pressure to return to normal.
AKT hopes to raise up t o pounds 25,000 by encouraging bars, clubs and LGBT societies to hold bucket collections, organise raffles or put on fundraising events to help raise much-needed cash t o improve support and services for some of the least fortunate members of the LGBT community.
The center's first objective, according to AKT president Wendell Blonigan, is to help Taiwanese manufacturers develop new CVD (chemical vapor deposition) manufacturing equipment and technologies.