AKAP6

AKAP6

A gene on chromosome 14q12 that encodes a member of the structurally diverse A-kinase anchor protein (AKAP) family, which binds to the regulatory subunit of protein kinase A (PKA), confining the enzyme to discrete locations within the cell. AKAP6 is highly expressed in certain regions of the brain and in cardiac and skeletal muscle; it localises to the sarcoplasmic reticulum and nuclear membrane, where it anchors PKA.
References in periodicals archive ?
For men, DNAJB5, RAC3, EAPP, HDLBP, PRG2, PER1, PIK31, and SLA2 were selected for validation, whereas for women the gene list for validation included AKAP6, LIMK1, SIRT7, ARHPGAP4, ATG16L2, TPM3, 5-HT1B, and PYGO2.
3]) and (B) performance of gene set consisting of ARHGAP4, AKAP6, PYGO2, HTR1B, ATG16L2, SIRT7, TPM3 and LIMK1 in women to distinguish between high (above 75th percentile corresponding to: 25.
Gene Gene description name Men DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 RAC3 Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) EAPP E2F associated phosphoprotein HDLBP High density lipoprotein binding protein (vigilin) PRG2 Proteoglycan 2 PER1 Period homolog 1 (Drosophila) PIK3R1 Phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) SLA2 Src-like adaptor 2 Women AKAP6 A kinase (PRKA) anchor protein 6 LIMK1 LIM domain kinase 1 SIRT7 Sirtuin (silent mating type information regulation 2 homolog) 7 (S.