DAX1

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Also found in: Acronyms.

DAX1

A gene (DSS-AHC critical region on the X chromosome, gene 1—formally known, per HUGO nomenclature, as NR0B1) located on chromosome Xp21.3 that encodes a protein containing a DNA-binding domain, which acts as a dominant-negative regulator of transcription mediated by the retinoic acid receptor. DAX1 also acts as an anti-testis gene by antagonising SRY.

Molecular pathology
DAX1 mutations cause both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
References in periodicals archive ?
Operational for just 9 months, AHX to date has over 775 members from 50 countries growing at a compounded rate of 10% a month, and has had over 50,000 transactions posted to its Exchange with a total market value in excess of $160 million.
AHX is the only global online marketplace dedicated exclusively to connecting aerospace hardware buyers and sellers.
Mascon's well earned reputation for technical excellence, dedicated customer service, and ability to get their partners to market quickly made them a natural choice for AHX," said Briand Greer, AHX's President.
AHX anticipates its web-based marketplace AHXonline to be operable in the 4th quarter of this year.