AHR

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AHR

A gene on 7p15 that encodes aryl hydrocarbon receptor, a ligand-activated transcription factor involved in cell cycle regulation and in regulating biological responses to planar xenobiotic halogenated aromatic hydrocarbons.
References in periodicals archive ?
The Ah-receptor protein contains a region characterized by a pattern of repeating amino acids, called the PAS domain.
However, Safe's studies now indicate that when the Ah-receptor lock is keyless, it will link up with another protein, known as Arnt.
The most unexpected dividends of Ah-receptor understanding may emerge in medicine.
Now we're developing a whole series of analogs of this vegetable-derived Ah-receptor activator for the treatment of breast cancer," he says.
These assays included two biochemical targets, tyrosine kinase and the proprietary Ah-receptor, and two cell-based assays, proprietary CDK1 and HIV cell fusion.
Babish reports that, "based upon the papers presented at the conference we anticipate no interference with common, nontoxic, naturally occurring, organic compounds that are capable of interacting with the Ah-receptor.
A human intervention study with foods containing natural Ah-receptor agonists does not significantly show AhR-mediated effects as measured in blood cells and urine.
The model Ah-receptor agonist beta-naphthoflavone inhibits aflatoxin B-1-DNA binding in vivo in rainbow trout at dietary levels that do not induce CYP1A enzymes.
Polybrominated diphenyl ethers (PBDEs) as Ah-receptor agonists and antagonists.