ANGPT1

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ANGPT1

A gene on chromosome 8q23.1 that encodes angiopoietin 1, a secreted glycoprotein which, like other angiopoietins, binds to endothelial cell-specific tyrosine-protein kinase receptor. It plays a key role in mediating interactions between the endothelium and surrounding matrix and mesenchyme, andit  inhibits endothelial permeability. Angiopoietin 1 plays a role in regulating angiogenesis; endothelial cell survival, proliferation, migration, adhesion and spreading; reorganisation of the actin cytoskeleton; and maintains vascular quiescence. It contributes to blood vessel maturation and stability and may be involved in cardiac embryogenesis.
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References in periodicals archive ?
The AGPT program is a postgraduate vocational training program required by medical graduates who want to become general practitioners.
The training devices include a new version of the existing virtual reality AGPT tactical tank trainer, termed the AGPT-S, which simulates the improved Leopard 2S tank and includes precision gunnery as well as tactical training capabilities.
Perceptronics is a second-tier subcontractor to Wegmann, to whom it has previously supplied AGPT simulator systems and components for the German Army.