AFP


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alpha

 [al´fah]
the first letter of the Greek alphabet, α; used to denote the first position in a classification system; as, in names of chemical compounds, to distinguish the first in a series of isomers, or to indicate the position of substituent atoms or groups; also used to distinguish types of radioactive decay, brain waves or rhythms, adrenergic receptors, and secretory cells that stain with acid dyes, such as the alpha cells of the pancreas.
alpha-adrenergic blocking agent (alpha-blocker) (alpha-blocking agent) any of a group of drugs that selectively inhibit the activity of alpha receptors in the sympathetic nervous system. As with beta-adrenergic blocking agents, alpha-blocking agents compete with the catecholamines at peripheral autonomic receptor sites. This group includes ergot and its derivatives, and phentolamine.
alpha chain disease the most common heavy chain disease, occurring predominantly in young adults in the Mediterranean area, and characterized by plasma cell infiltration of the lamina propria of the small intestine resulting in malabsorption with diarrhea, abdominal pain, and weight loss, or, exceedingly rarely, by pulmonary involvement. The gastrointestinal form is immunoproliferative small intestine disease.
alpha-fetoprotein (AFP) a plasma protein produced by the fetal liver, yolk sac, and gastrointestinal tract and also by hepatocellular carcinoma, germ cell neoplasms, and other cancers in adults; elevated levels may also be seen in benign liver disease such as cirrhosis and viral hepatitis. The serum AFP level is used to monitor the effectiveness of cancer treatment.

During pregnancy some AFP crosses from the amniotic fluid to the mother's blood. If the fetus has a neural tube defect, large amounts of AFP will be found in the amniotic fluid and maternal blood. Blood screening tests for serum AFP can thus be done as a first step in the screening process; if test results are positive, further testing is indicated to diagnose the defect.
alpha particles a type of emission produced by the disintegration of a radioactive substance. The atoms of radioactive elements such as uranium and radium are very unstable, continuously breaking apart with explosive violence and emitting particulate and nonparticulate types of radiation. The alpha particles, consisting of two protons and two neutrons, have an electrical charge and form streams of tremendous energy when they are released from the disintegrating atoms. These streams of energy (alpha rays) can be used in treatment of various malignancies. See also radiation and radiation therapy.

AFP

Abbreviation for α-fetoproteins. See: fetoproteins.

AFP

alpha fetoprotein.

AFP

abbr.
alpha-fetoprotein

AFP

abbreviation for alpha-fetoprotein.

AFP

A gene on chromosome 4q11-q13 that encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during foetal life. AFP is regarded as the foetal counterpart of serum albumin and binds copper, nickel, fatty acids and bilirubin; hereditary persistance of alpha-fetoprotein may be found in individuals with no obvious pathology.

Molecular pathology
AFP is elevated in foetuses with neural tube defects, including spina bifida and anencephaly. It is elevated in adults with hepatocellular carcinomas and germ cell tumours.

AFP

α-fetoprotein, see there.

AFP

Abbreviation for alpha(α) fetoprotein test.

AFP (Alpha-fetoprotein)

A tumor marker associated with liver, testicular, and ovarian cancer.
Mentioned in: Tumor Markers

AFP

alpha-fetoprotein.
References in periodicals archive ?
Dashe's team offered AFP screening between 15 and 21 weeks of gestation and performed specialized ultrasound for patients with an AFP of at least 2.
Neither the detection of the new viruses in two SIDS cases nor the reported link between maternal AFP levels and SIDS qualify as breakthroughs in understanding SIDS, she said.
To test for heterophilic antibodies, we measured AFP in eight sera before and after incubation in Heterophilic Blocking Tubes (Scantibodies Laboratories Inc.
What skills did you gain as a result of the AFP certification process?
6 billion contribution remitted earlier this year for the AFP Modernization Program, for a total of P4.
There are two possible reasons why politicians in our country prefer the revolving-door concept over the fixed term for an AFP chief of staff.
It's very satisfying for AFP Foundation to work in partnership with twofour54 tadreeb to contribute to this growth and we look forward to developing courses especially tailored for journalists here," he added.
AFP said we have already initiated legal action against all the individuals involved in this unconstitutional activity.
The buyers announced the transaction separately for USD516m in total, with each taking 50% in AFP Horizonte.
Babu also told AFP that the operation uncovered a Boko Haram weapons store containing 300 explosive devices and two dozen AK-47 rifles.
Dr Jacob, also a member of the national technical advisory group on immunisation and of the working group on food and drug regulation in the 12th five-year plan, said that there was a definite co-relation between the increase in the number of AFP and the irrational administration of OPV.
As AFP surveillance systems matured, countries increasingly applied AFP surveillance strategies and infrastructure to detect other diseases (2).