They dug deeper to prove whether chlorophyllin directly inhibited AFB1 absorption into the body.
When the volunteers took a 150 mg dose of chlorophyllin along with the AFB1, AFB1 absorption rate into the bloodstream decreased drastically and the urine output of the AFB1-induced DNA damage compound was reduced.
Once scientists knew that chlorophyllin could reduce the absorption of AFB1, they took the research a step further to find out if the protective effects of chlorophyllin against DNA damage would contribute to reduced liver tumor formation.
In order to determine this, researchers gave rats AFB1 plus chlorophyllin (250 mg/kg body weight) five times per day for three days, while other rats were given AFB1 plus a placebo.
Banlunara (2005) indicated that activities of ALP and GGT were increased by AFB1, and were decreased by EGM.
2008) indicated that HSCAS ameliorated the adverse effects of AFB1 on some of the serum chemistry pamameters, increased antioxidant capacity in liver, and reduced the severity of hepatic microscopic lesions due to AFB1.