ARF protein

(redirected from ADP ribosylation factor)
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ARF protein

Any of a family of small G proteins involved in vesicle trafficking, so named for their ability to support ADP-ribosylation of the trimeric G protein, Gs, which is an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase involved in protein trafficking. ARFs act by vesicle budding from Golgi cisternae and other membrane compartments, and mediate GTP-dependent stimulation of phospholipase D.
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