ADME


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ADME

abbreviation for the time course of drug distribution, representing the terms absorption, distribution, metabolism, and elimination.

ADME

An acronym for the 4 phases—absorption, distribution, metabolism, excretion—which describe pharmacokinetics in mammals.
References in periodicals archive ?
During the past 15 or more years, the availability of relatively high-throughput ADME assays has generated vast amounts of data within large pharmaceutical companies, but with little improvement in success rates.
Barrett T, Visser IKG, Mamaev L, Goatley L, Van Bressem MF, Osterhaus ADME.
ADME-Enabling Technologies in Drug Design and Development focuses on the current state of the art in the field, presenting a comprehensive review of the latest tools for generating ADME data in drug discovery.
Specifically, ADME Database includes metabolic information and kinetic parameter information on cytochrome P450, a drug metabolizing enzyme, and information on transporter substrates.
Celerion, the premier provider of innovative early stage drug development solutions, is pleased to announce that it has expanded its ADME (Absorption, Distribution, Metabolism and Excretion) Suite in Lincoln, Nebraska USA.
Just as Cyprotex's in silico and in vitro ADME services were at the forefront of reducing inefficiencies due to ADME, the Company is now at the forefront of applying the same technologies to the growing problem of toxicity'.
Scientists interested in analyzing ADME genes can now look far beyond what existing genotyping panels reveal and discover the novel chromosomal changes and rare variants associated with drug metabolism and molecular pharmacology," said Andy Watson, Ph.
Under this new contract, O2h will also provide ADME services to Sentinel Oncology.
This book answers the need to regularize the drug discovery interface; it defines and reviews the field of ADME for medicinal chemists.
MACCLESFIELD, England, August 20, 2010 /PRNewswire/ -- Cyprotex PLC (LSE:CRX), the preclinical ADME Tox services company, today announces the launch of its new in vitro toxicology service, branded as Cyprotox(R).
As part of the collaboration, RainDance and 454 Life Sciences plan to commercially launch a core ADME gene screening research panel that will address one of the large unmet research needs in academic, pharmaceutical and biotechnology markets.
NEW YORK, April 20, 2015 /PRNewswire/ -- This report analyzes the worldwide markets for ADME-Toxicology Testing in US$ Million by the following Segments: Toxicology Testing (In-Vivo, & In-Vitro), and ADME Testing.