ADH6

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ADH6

A gene on chromosome 4q23 that encodes class-V alcohol dehydrogenase, which like other alcohol dehydrogenases metabolises various substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids and lipid peroxidation products. It is expressed in the stomach and liver, and has a glucocorticoid response element upstream of its 5' UTR.
References in periodicals archive ?
The ADH-5 [TM] Multiplex IHC (Biocare Medical) supports the differentiation of UDH from ADH.
Badve's study reduces the incidence of ADH based on use of the ADH-5 Multiplex IHC test, which is consistent with the literature, as it is well known that ADH is overdiagnosed.
After native gel electrophoresis, the three isozymes of ADH, namely, ADH-5 (no NAD-acetone complex bound), ADH-3 (one-bound complex), and ADH-1 (both active sites occupied with NAD-acetone compounds), could be observed.
A comprehensive panel of antibodies for breast carcinoma includes ADH-5 (atypical ductal hyperplasia).