1,004,851,964 visitors served.
1,004,851,964 visitors served. |
|
 Dictionary/ thesaurus |  Medical dictionary |  Legal dictionary |  Financial dictionary |  Acronyms |  Idioms |  Encyclopedia |  Wikipedia encyclopedia | ? |
ADCC |
Also found in: Acronyms, Wikipedia | 0.06 sec. |
|
ADCC antibody-dependent cell-mediated cytotoxicity. ADCC antibody-dependent cell-mediated cytotoxicity. |
|
? Mentioned in | ? References in periodicals archive | |
|---|---|---|
It is based on an active modulation
of antibody glycosylation during production leading to antibody products
with increased ADCC (antibody-dependent cellular cytotoxicity). Two receptors found to predict ADCC activation and improved outcome
to rituximab,(2,3) known as Fc(gamma)RIIIa 158V/F and Fc(gamma)RIIa 131
H/R, were also found to be potential molecular markers for ADCC
activation and improved clinical outcome of patients treated with single
agent ERBITUX. Pre-clinical data presented on ERBITUX, an IgG1 monoclonal antibody
(MAb), included a study examining the IgG1 MAb-mediated anti-tumor
effects known as ADCC (antibody-dependent cell-mediated cytotoxicity),
or the recruitment of the body's immune defenses to attack cancer
cells. |
 |
| Free Tools: |
For surfers:
Browser extension |
Word of the Day |
Help
For webmasters: Free content NEW! | Linking | Lookup box | Double-click lookup | Partner with us |
|
|---|
Disclaimer |
Privacy policy |
Feedback | Copyright © 2008 Farlex, Inc.
Printer friendly
Cite / link
Email
Feedback
Add definition
ADCC
