APP

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APP

amyloid precursor protein.

APP

abbr.
amyloid precursor protein

amyloid precursor protein (APP)

a large transmembrane glycoprotein expressed on the cell surface and of uncertain function; it may be cleaved on the cell surface to a soluble form. Alternatively, cleavage may follow endocytosis and in some cases then yields 40 to 43 abnormal amino acid peptides, which aggregate to form Ab amyloid, associated with Alzheimer's disease.

APP

A gene on chromosome 21q21.3 that encodes a cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form various peptides.

Molecular pathology
APP mutations are implicated in autosomal dominant Alzheimer’s disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).

APP

Amyloid β protein precursor A membrane-spanning glycoprotein of unknown function, which is expressed in many mammalian tissues, the gene for which maps to chromosome 21. See Alzheimer's disease, β-amyloid.
References in periodicals archive ?
The AD1 and another PO1 mech went inside to inform Maintenance Control.
Water Mean [+ or -] SD RSD Participant system TCAA ([micro] g/day) (%) AD1 Anstey Hill Ingestion 41 [+ or -] 27 67 Excretion 5.
The AD1 tried to help, but he couldn't reach anything from his position because of the small size of the compartment.
Analise quimica dos carvoes e composicao das misturas em base seca (% em massa) Amostra Cz MV Stotal ABC1 ABC2 A 7,99 37,03 0,83 50 40 B 7,39 37,06 1,73 10 20 C 9,16 12,40 0,26 40 40 D 5,38 I9,67 0,77 -- -- Amostra ABC3 ABC4 AD1 AD2 AD3 A 30 20 60 50 40 B 30 40 -- -- -- C 40 40 -- -- -- D -- -- 40 50 60 Cz: Cinzas; MV: Materia volatil.
It is believed that an ancient tribe, the Corieltauvi, who lived in Britain before the Roman conquest, killed and then buried the dog between AD1 and AD50 so its spirit could protect the stockpile, reports the Daily Mail.
About his upcoming projects, he said: "At the moment, I'm in Mombasa, a coastal town in Kenya dating from AD1,600.
Some 420 years later, embittered descendant Sir Piers Pomfrey (Tennant again), leader of a secret brethren of 'women-hating psychopaths' called AD1, exacts his revenge by seeking the two rings, which together reveal the location of the plundered treasure.
Mobile Phone Examiner Plus Software offers the following features: supports more than 2500 phones; extracted data is stored in AD1 forensic container; and AD1s can be imported back into MPE+ to view data as if the device is connected.
The author: AD1 Grogan is attached to Commander Naval Air Forces Reserve (CNAFR) Aviation Safety in Norfolk
Some 420 years later, embittered descendant Sir Piers Pomfrey (Tennant again), leader of a secret brethren of "women-hating psychopaths" called AD1, exacts his revenge by seeking the two rings which give the location of the plundered treasure.
Some 420 years later, embittered descendant Sir Piers Pomfrey (Tennant again), leader of a secret brethren called AD1, exacts his revenge by seeking the two rings which give the location of the plundered treasure.