ACTN3

ACTN3

A gene on chromosome 11q13-q14 that encodes an actin-binding bundling protein expressed only in skeletal muscle, which localises to the Z-disc and analogous dense bodies, where it helps to anchor the myofibrillar actin filaments.
Mentioned in ?
References in periodicals archive ?
Almost nine years ago, some Australian scientists had come up with a study that black sprinters have a gene called ACTN3 which is involved in fast muscle twitching.
Scientists have also found that there are certain natural variants of a gene called ACTN3 that can boost the performance of fast-twitch muscle fibres.
2009) Strength, power, fiber types, and mRNA expression in trained men and women with different ACTN3 R577X genotypes.
Usain Bolt's sprint achievements at Beijing in 2008 and Berlin in 2009 will doubtless advance this case, with some absurd claims in many newspapers, in Australia and abroad, about Jamaican 'unfairness' in having so much of the allegedly jet-propelling, fast-twitch muscle protein ACTN3 gene.
Differences in ACTN3 genotypes have been found between endurance and sprint athletes (4).
For example, people who have two copies of a gene called ACE have been found to have three to five times the heart capacity of those with one copy of the gene; a mutation in a gene called ACTN3 increases fast-twitch fibres necessary for sprinting; and a mutation in HIF-1a allows superior adaptation to low-oxygen conditions.
Australian researchers identified two versions of a gene called alpha-actinin-3,or ACTN3,New Scientist magazine reported.
Whether you're better suited to run a marathon or a 100-meter sprint correlates with a gene called ACTN3, researchers find.
The ACTN3 is a protein specific to the type 2 fibers (Beggs et al.
The test allows parents to take a swab from their child's mouth and then send off the sample to a laboratory to test for ACTN3, a gene found to have links with athletic success.
MELBOURNE, Australia -- Genetic Technologies Limited ("GTG") (NASDAQ:GENE)(ASX:GTG) announces the official launch of its ACTN3 SportsGene Test(TM) in Japan.