ACTG


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ACTG

AIDS Clinical Trials Group. An HIV/AIDS clinical trials organisation established in 1987 to broaden the scope of the AIDS research effort of the US National Institute of Allergy and Infectious Diseases (NIAID). The ACTG supports the largest network of expert clinical and translational investigators and therapeutic clinical trials units in the world, including sites in resource-limited countries, whose investigators and units serve as the major resource for HIV/AIDS research, treatment, care, and training/education in their communities. It has been pivotal in providing the data necessary for approval of therapeutic agents, as well as the treatment and prevention strategies for many opportunistic infections and malignancies. The ACTG is composed of, and directed by, leading clinical scientists in HIV/AIDS therapeutic research and funded by the US Department of Health and Human Services, NIH through the NIAID.

ACTG

Abbrev for . AIDS Clinical Trials Group. This is a large US government-sponsored organisation dedicated to research into the treatment of AIDS.
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The results of the ACTG Phase II/III study will be submitted by Unimed to the FDA.
We are pleased that after an extensive review of NTZ, the ACTG chose to study it in treating cryptosporidial diarrhea," said Stephen M.
ACTG 116B/117 investigators reported that patients who were randomized to VIDEX at 500 mg/day -- which correlates to the currently recommended dose -- had a statistically significant delay in time to first new AIDS defining event or death compared to those randomized to AZT.
In April 1992, an FDA advisory panel reviewed the preliminary results of ACTG 116B/117 and agreed that the clinical benefits of VIDEX had been confirmed.
In ACTG 116B/117, VIDEX was well tolerated in the majority of patients.