ACE


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angiotensin

 (ACE) [an″je-o-ten´sin]
a vasoconstrictive substance formed in the blood when renin is released from the juxtaglomerular apparatus in the kidney. The enzymatic action of renin acts on angiotensinogen to form the decapeptide angiotensin I, which is relatively inactive. It in turn is acted upon by peptidases (converting enzymes), chiefly in the lungs, to form the octapeptide angiotensin II, a powerful vasopressor and a stimulator of aldosterone secretion by the adrenal cortex. By its vasopressor action, it raises blood pressure and diminishes fluid loss in the kidney by restricting blood flow. Angiotensin II is hydrolyzed in various tissues to form heptapeptide angiotensin III, which has less vasopressor activity but more effect on the adrenal cortex.
angiotensin-converting enzyme (ACE) an enzyme of the hydrolase class that catalyzes cleavage of a dipeptide from the C-terminal end of angiotensin I to form activated angiotensin II; called also peptidyl-dipeptidase A.
angiotensin-converting enzyme inhibitors competitive inhibitors of angiotensin-converting enzyme, which converts angiotensin I to angiotensin II and inactivates bradykinin. ACE inhibitors, such as captopril, are antagonists of the renin-angiotensin-aldosterone system and potentiators of the kinin system and are used for treatment of hypertension, usually in conjunction with a diuretic. They are also used as vasodilators in the treatment of congestive heart failure.

ACE

ACE

ACE

(1) Abciximab & Carbostent Evaluation in Acute Myocardial Infarction. A trial comparing outcomes of carbon-coated stenting of an infarct-related artery with and without abciximab.
Primary endpoint 30-day MACE (major acute coronary events)
Conclusion Abciximab + IRA stenting may be a viable reperfusion strategy in patients with acute myocardial infarction undergoing primary percutaneous revascularization.
(2) ASA & Carotid Endarterectomy. A trial comparing high- and low-dose aspirin to reduce the risk of stroke in patients undergoing carotid endarterectomy.
Primary endpoints 30-day MACE (major acute coronary events), stroke
Conclusion Low-dose (80, 325 mg) ASA patients did better

ACE

Angiotensin-converting enzyme, see there. Cf ACE inhibitors, also
1. Acute Care for Elderly.
2. Adriamycin, cyclophosphamide, etoposide.
3. Alcohol, chloroform, ether–obsolete anesthetic cocktail.
4. American College of Epidemiology.

ACE

Abbreviation for angiotensin-converting enzyme.

ACE

See ANGIOTENSIN-CONVERTING ENZYME.

ACE

angiotensin converting enzyme

ACE,

ACE

angiotensin-converting enzyme.

ACE inhibitors
a group of drugs used as vasodilators in the management of heart failure. They act to decrease circulating levels of angiotensin II and aldosterone. See captopril, enalapril, lisinopril.

ace

acepromazine.
References in periodicals archive ?
We're now making this a major division within Ace," he said.
The Late Great Johnny Ace and the Transition from R&B to Rock 'n' Roll.
Like radar, Ace zeroes in on her, saying, "That's quite a wrap you're wearing.
One component of the ACE adjustment is an umbrella provision that disallows deductions that are not permitted in determining earnings and profits (E&P).
As exhibit 2 ACE computation schedule shows, the ACE calculation starts with AMTI before AMT net operating losses or the ACE adjustment (tentative AMTI), and then a series of adjustments is made to arrive at ACE.
This article discusses the newly enacted changes of the Revenue Reconciliation Act of 1989 and compares them to the ACE provisions previously scheduled to go into effect but now dropped from the AMT rules.
While hiring Ace to find the missing dolphin, the team's owner keeps calling the dolphin a "fish," and Ace keeps correcting him that it's a mammal.
Petalas brings to ACE over 25 years of diverse experience in the reinsurance arena.
Established in 2006, ACE Life Insurance, Russia is a wholly owned subsidiary of ACE European Holdings No 2 Limited, a UK-based holding entity of the ACE Group of Companies.
For more information about the full range of ACE USA's environmental liability products and services, please contact Andrew Steneri, Assistant Vice President, ACE Environmental Risk, Northeast Region at (617) 737-8931 or Andrew.
Best has upgraded the FSR to A+ (Superior) from A (Excellent) and the ICR to "aa-" from "a+" of ACE European Group Limited (AEGL) (United Kingdom).