ACAM2000

ACAM2000

A live smallpox vaccine manufactured from vaccinia cell cultures (a related orthopoxvirus).
References in periodicals archive ?
Currently unlicensed third-generation smallpox vaccines may be considered (pending licensure) as replacements to ACAM2000 (Sanofi Pasteur Biologics, Lyon, France), the currently licensed vaccinia vaccine, for laboratory workers at national variola testing sites or perhaps an even broader population of laboratory workers throughout the United States.
Another example is also the Acambis ACAM2000 smallpox vaccine which is made in a Vero cell line using disposable production technology.
Vaccinia virus was confirmed in all four patients, and gene sequencing in three of the cases linked the virus to the ACAM2000 smallpox vaccine.
The Food and Drug Administration has approved a new smallpox vaccine, ACAM2000, for active immunization against smallpox in individuals determined to be at high risk for smallpox infection.
In May, the Food and Drug Administration's Vaccines and Related Biological Products Advisory Committee voted 11-0 in favor of both the safety and efficacy of the vaccine, marketed as ACAM2000.
The panel agreed unanimously that the vaccine, ACAM2000, would protect people considered at high risk of exposure in a smallpox outbreak.
Shares in Acambis, who are best known for developing the smallpox vaccine ACAM2000, rose three per cent yesterday
Acambis is best known for vaccines such as ACAM2000, which inoculates peopleagainst smallpox and has been stockpiled by the US Government
Revenues in the period reflected the existing ACAM2000 US Government contract
Shares in Acambis lost a nasty 13 per cent yesterday when it said it was suspending clinical trials of ACAM2000 after some patients got a heart inflammation known as myopericarditis.
The second-generation vaccine is ACAM2000 (Acambis, Cambridge, MA, USA), which is a plaque-purified distinct strain of New York City Board of Health vaccinia virus grown by using modern cell lines rather than the skin of calves.
Acambis' ACAM2000 (Smallpox (Vaccinia) Vaccine, Live) vaccine for active immunization against smallpox disease for persons determined to be at high risk for smallpox infection was licensed by the US Food and Drug Administration in August 2007.