ACAD9

ACAD9

A gene on chromosome 3q21.3 that encodes a dehydrogenase three times more active on palmitoyl-CoA than on stearoyl-CoA. ACAD9 is ubiquitously expressed in most normal human tissues and cancer cell lines, especially in heart, skeletal muscles, brain, kidney and liver.

Molecular pathology
Defects in ACAD9 cause isobutyryl-CoA dehydrogenase deficiency.
References in periodicals archive ?
05--indicated that ACSL1, ABCA1, DHCR24, ACAT2, ACACA, ABCG1, ACAD9, ACACB, IDI1, PPARG, SCD, SCARB1, HMGCS1, EBP, DHCR7, FASN, HMGCR, and GPAM were down-regulated upon G treatment; whereas NR1H2, PPARA, INSIG2, CPTP1, APOE, VLDLR, ABCC2, and SREBF2 were activated after exposure to G (Fig.