lopinavir

(redirected from ABT-378)
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lopinavir

 [lo-pin´ah-vir]
an HIV protease inhibitor, an antiviral agent used in combination with ritonavir in the treatment of human immunodeficiency virus infection; administered orally.

lopinavir

/lo·pin·a·vir/ (lo-pin´ah-vir) an antiviral HIV protease inhibitor, used with ritonavir in the treatment of HIV infection.

lopinavir

[lopin′ävir]
an HIV protease inhibitor, an orally administered antiviral agent used in combination with ritonavir in the treatment of human immunodeficiency virus infection.

lopinavir

An antiretroviral protease inhibitor with potent anti-HIV effect in clinical studies.
 
Adverse effects
Headache, diarrhea.
References in periodicals archive ?
In a partially blinded study, 70 patients who had failed their first PI and had never taken nonnucleoside reverse transcriptase inhibitors (NNRTIs) took ABT-378 for 2 weeks, then added nevirapine and two NNRTIs.
Other studies employed PhenoSense HIV to measure resistance to novel protease inhibitors ABT-378 and BMS 232632.
For example, Abbott Laboratories has a new-generation protease inhibitor known as ABT-378 that in lab tests has shown itself to be more powerful than the protease inhibitors on the market.