APP

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APP

amyloid precursor protein.

APP

abbr.
amyloid precursor protein

amyloid precursor protein (APP)

a large transmembrane glycoprotein expressed on the cell surface and of uncertain function; it may be cleaved on the cell surface to a soluble form. Alternatively, cleavage may follow endocytosis and in some cases then yields 40 to 43 abnormal amino acid peptides, which aggregate to form Ab amyloid, associated with Alzheimer's disease.

APP

A gene on chromosome 21q21.3 that encodes a cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form various peptides.

Molecular pathology
APP mutations are implicated in autosomal dominant Alzheimer’s disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).

APP

Amyloid β protein precursor A membrane-spanning glycoprotein of unknown function, which is expressed in many mammalian tissues, the gene for which maps to chromosome 21. See Alzheimer's disease, β-amyloid.
References in periodicals archive ?
Under the terms of the agreement, ABPP at its election may request a two year extension of the repayment date from July 2012 to July 2014, subject to meeting criteria including Loan to Value, Interest Cover and Net Worth covenants.
D, ABPP, 5440 Flint Tavern Place, Burke, Virginia 22015; pscrofani@ipsciences.
However, that discussion is now largely academic as APA, ABPP, state regulatory bodies and numerous other profession shaping forces in psychology have formally embraced specialization models (Roberts, 2006).
James Dobbins, PhD, ABPP, is a professor in the School of Professional Psychology.
are affected by diabetes and 1 out of every 8 African Americans has diabetes, so the need for effective programs and focused research is great," said Felicia Hill-Briggs, PhD, ABPP, professor at The Johns Hopkins University School of Medicine, and American Diabetes Association board member.
Norcross, PhD, ABPP, is an internationally recognized expert on behavior change and undisputed authority on New Year's resolutions.
Jerrold Pollak, PhD, ABN, ABPP, is a clinical and neuropsychologist in the program in Medical and Forensic Neuropsychology and the Emergency Services Department of Seacoast Mental Health Center, Portsmouth, N.
For another, Gerald Corey, EdD, ABPP, will be speaking Saturday afternoon on "The Counselor as a Person and as a Professional.
DiClemente, PhD, ABPP, presents case studies that illustrate how medications have helped individuals break their dependence on alcohol.
ABPP President, American Board of Behavioral Psychology, Inc.
ABPP, FAPFP, Editor of Education, and Director of The Cassel Institute, Chula Vista.
Geri Miller, PhD, Diplomate in Counseling Psychology, ABPP, is a Full Professor in the Department of Human Development and Psychological Counseling at Appalachian State University.