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Related to ABO incompatibility: Coombs test
ABO IncompatibilityA type of blood incompatibility in which recipients—e.g., those with genotypes AO, BO, OO—of donated blood products, usually understood to mean packed red cells, have antibodies to antigens A or B on the surface of red cells being transfused.
ABO incompatibilityTransfusion medicine A type of blood incompatibility, in which certain recipients–eg genotypes AO, BO, OO of donated blood products-usually understood to mean packed RBCs, has antibodies to antigens–A or B on the surface of RBCs being transfused. See ABO system.
Obstetrics: Transplacental fetal-maternal transfusion occurs when fetal blood cells escape into the maternal circulation, eliciting antibody formation. Maternal antibodies then cross the placenta into the fetal circulation, attack, and destroy red blood cells, as evidenced by neonatal hyperbilirubinemia and jaundice.