ABL2


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ABL2

A gene on chromosome 1q25.2 that encodes a member of the Abelson family of nonreceptor tyrosine protein kinases, which is highly homologous to ABL1, has tyrosine kinase, SH2 and SH3 domains, and plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences.
References in periodicals archive ?
Mr Zwiers was previously senior process manager at ABL2 and programme manager at the Brabantse Ontwikkelings Maatschappij.
The 1q25 probe contains sequences extending from a point telomeric to the WI-6848 locus, through the ABL2 and ANGPTL1 genes, and ending proximally near SHGC-1322.