ABCD trial

ABCD trial

Cardiovascular disease
1. A prospective, randomized, blinded, clinical trial–Appropriate Blood Pressure Control in Diabetes–which compared, in type 2–NIDDM diabetics, 1. The efficacy of nisoldipine, a CCB, with enalapril, an ACE inhibitor, as 1st-line antihypertensive agents and.
2. The effects of moderate BP control–target–80-89 mm Hg vs 'tight' BP control–target–75 mm Hg on cardiovascular M&M. See Enalapril, Nisoldepine.
3. A clinical trial–Alternans Before Cardioverter-Defibrillator.
References in periodicals archive ?
The first five years of the ABCD trial involved controlling blood pressure with an angiotensin converting enzyme(ACE) inhibitor and a calcium channel blocker.
Results of the first five years of the trial have provided important information about preventing heart attacks using ACE inhibitors to lower blood pressure in diabetic patients," said Robert Schrier, MD, principal investigator of the ABCD trial and chairman of the Department of Medicine at the CU-Health Sciences Center.
The ABCD Trial found that a non-invasive test called microvolt T-Wave Alternans (which uses computer technology to predict a patient's risk for sudden cardiac death) is comparable to an invasive and more expensive procedure commonly used by cardiac electrophysiologists to determine a patient's eligibility for an implanted defibrillator.
The ABCD trial will give referring physicians a non-invasive means of categorizing a patient's risk," said Eric S.